The purpose of this study to compare of clinical profile between obese and nonobese type 2 diabetic patients.
The subjects were consist of 111 obese(50 male, 61 female) and 159 nonobese(79 male, 80 female) type 2 diabetic patients underwent fasting blood glucose, 2-hour postprandial blood glucose, HbA₁c, total cholesterol, triglyceride, high density lipoprotein, microalbuminuria, fasting C-peptide and 2-hour postprandial C-peptide were measured. Diabetes was diagnosed according to the American Diabetes Association(ADA)criteria. Obesity was defined as body mass index(BMI, kilograms per meters squared)≥23.
Data analysis were t-test, chisquare test in SAS program.
The results were as follows :
1) Triglycerides and 2-hour postprandial C-peptide were significant higher in obese than nonobese patients.
2) Systolic blood pressure, Diastolic blood pressure, fasting blood sugar, 2-hour postprandial blood glucose, HbA₁c, total cholesterol, high density lipoprotein, microalbuminuria and fasting C-peptide were no difference between obese and nonobese groups.
These data indicate that obesity is a risk factor for the development of coronary heart disease(CHD) in diabetic patients. Therefore, weight reduction have beneficial effects on insulin action and glycemic control in obese type 2 diabetic patients.
제2형 당뇨병,비만,중성지방,식후 2시간 C-peptide,type 2 diabetes mellitus,obesity,triglyceride,C-peptide
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