pISSN : 2383-6415   eISSN : 2383-6423

Antioxidant Capacity and Associated Factors during the Chronic Phase after Stroke



INFORMATION : page. 52~59 / 2014 Vol.16 No.1


뇌혈관 질환은 우리나라 사망원인 2위이며, 단일질환으로는 1위 이다(Lee et al., 2012). 또한 뇌혈관 질환은 생존한다 하더라도 재발 위험이 높다. 뇌졸중은 발생 후 관리가 중요한 것으로 알려져 있는데, 그 이유는 뇌졸중 발병 후 첫해 안에 심혈관계 질환에 걸릴 위험이 일반인에 비해 15배 증가하고, 20-40%의 환자가 뇌졸중 발병 후 5년 안에 뇌졸중 재발을 경험한다는 보고 때문이다.

Purpose: The purpose of this study was to investigate antioxidant capacity and relating factors including gender, obesity, lifestyle factors, and nutrient intake in chronic stroke patients. Methods: A total of 188 chronic stroke patients who visited a medical center in Seoul participated in the study. A structured questionnaire was used to assess their clinical characteristics and lifestyles. Blood samples were collected for ferric reducing ability of plasma (FRAP) for antioxidant capacity. Dietary intake of the patients were obtained for 2 days by 24 hours recall method. Results: The mean FRAP was 392.0μmol/L. According to the hierarchical multiple regression analysis, the factors related to high FRAP were male sex (p=.036), alcohol drinking (p=.013), and calorie intake deficiency (p=.005). Conclusion: We found that antioxidant capacity was related to lifestyle factors including alcohol drinking, and calorie intake in chronic stroke patients. A tailored strategy is needed to increase antioxidant capacity according to gender and lifestyles in the chronic phase of stoke patients.

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